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The human intrauterine environment in the presence of a progesterone-releasing device has been studied. Drugs from this class can cause serious side effects such as heart disease (including heart attack and heart failure), formation of blood-filled cysts or tumors in the liver, water retention (with swelling of ankles and feet, shortness of breath, and weight gain), kidney disease, stroke, mental health problems (including anxiety, depression, anger, trouble sleeping, abnormal drug-seeking behaviour), nausea, vomiting, headache, change in sexual interest, acne, high blood pressure, breathing problems, jaundice, high blood calcium levels (with vomiting, stomach pain, increased thirst or urination, muscle pain or weakness, joint pain), high blood fat levels, and allergic reactions (with rash, swelling of face, tongue, throat, and difficulty breathing).

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These compounds are being prescribed increasingly by some physicians to treat their HIV-infected patients. This is why Sustanon is also used regularly during cutting phases, too. These substances, a kind of precursor to a hormone (rather than a hormone itself), can amplify the effect of existing hormones. Oxandrin was discontinued to assess the possibility of a anabolic steroid-induced singultus. The investigation suggests that supraphysiological doses of anabolic steroids stimulate significant alterations in muscle size and muscle strength, especially when taken in conjunction with a progresive resistance training programm. Liver enzyme rose significantly in the oxymetholone group, but the number of values greater than three times the upper limit of normal were not different between these groups.

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